Secondary Structure of rhBMP-2 in a Protective Biopolymeric Carrier Material
نویسندگان
چکیده
منابع مشابه
Secondary structure of rhBMP-2 in a protective biopolymeric carrier material.
Efficient delivery of growth factors is one of the great challenges of tissue engineering. Polyelectrolyte multilayer films (PEM) made of biopolymers have recently emerged as an interesting carrier for delivering recombinant human bone morphogenetic protein 2 (rhBMP-2 noted here BMP-2) to cells in a matrix-bound manner. We recently showed that PEM made of poly(l-lysine) and hyaluronan (PLL/HA) ...
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15 صفحه اولFabrication and release behavior of a novel freeze-gelled chitosan/gamma-PGA scaffold as a carrier for rhBMP-2.
OBJECTIVE The aim of this study was to fabricate a novel composite porous scaffold by blending chitosan and gamma-poly(glutamic acid) (gamma-PGA) for the sustained delivery of rhBMP-2. METHODS Chitosan and gamma-PGA were blended to fabricate a novel porous scaffold by the freeze-gelation method. For comparison, scaffolds made of freeze-dried chitosan, freeze-dried PLLA, and freeze-gelled chit...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2012
ISSN: 1525-7797,1526-4602
DOI: 10.1021/bm3010808